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The Importance of TM3-4 Loop Subdomains for Functional Reconstitution of Glycine Receptors by Independent Domains

Truncated glycine receptors that have been found in human patients suffering from the neuromotor disorder hyperekplexia or in spontaneous mouse models resulted in non-functional ion channels. Rescue of function experiments with the lacking protein portion expressed as a separate independent domain d...

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מידע ביבליוגרפי
Main Authors: Unterer, Bea, Becker, Cord-Michael, Villmann, Carmen
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493960/
https://ncbi.nlm.nih.gov/pubmed/22995908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.376053
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