Single Expressed Glycine Receptor Domains Reconstitute Functional Ion Channels without Subunit-specific Desensitization Behavior

Cys loop receptors are pentameric arrangements of independent subunits that assemble into functional ion channels. Each subunit shows a domain architecture. Functional ion channels can be reconstituted even from independent, nonfunctional subunit domains, as shown previously for GlyRα1 receptors. He...

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Autori principali: Meiselbach, Heike, Vogel, Nico, Langlhofer, Georg, Stangl, Sabine, Schleyer, Barbara, Bahnassawy, Lamia'a, Sticht, Heinrich, Breitinger, Hans-Georg, Becker, Cord-Michael, Villmann, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200267/
https://ncbi.nlm.nih.gov/pubmed/25143388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559138
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