Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression

Concurrent activation of RAS/ERK and PI3K/AKT pathways is implicated in prostate cancer progression. The negative regulators of these pathways, including sprouty2 (SPRY2), protein phosphatase 2A (PP2A), and phosphatase and tensin homolog (PTEN), are commonly inactivated in prostate cancer. The molec...

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Bibliografiske detaljer
Main Authors: Patel, Rachana, Gao, Meiling, Ahmad, Imran, Fleming, Janis, Singh, Lukram B., Rai, Taranjit Singh, McKie, Arthur B., Seywright, Morag, Barnetson, Robert J., Edwards, Joanne, Sansom, Owen J., Leung, Hing Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582117/
https://ncbi.nlm.nih.gov/pubmed/23434594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63672
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