Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression

Concurrent activation of RAS/ERK and PI3K/AKT pathways is implicated in prostate cancer progression. The negative regulators of these pathways, including sprouty2 (SPRY2), protein phosphatase 2A (PP2A), and phosphatase and tensin homolog (PTEN), are commonly inactivated in prostate cancer. The molec...

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Hauptverfasser: Patel, Rachana, Gao, Meiling, Ahmad, Imran, Fleming, Janis, Singh, Lukram B., Rai, Taranjit Singh, McKie, Arthur B., Seywright, Morag, Barnetson, Robert J., Edwards, Joanne, Sansom, Owen J., Leung, Hing Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582117/
https://ncbi.nlm.nih.gov/pubmed/23434594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63672
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