Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression

Concurrent activation of RAS/ERK and PI3K/AKT pathways is implicated in prostate cancer progression. The negative regulators of these pathways, including sprouty2 (SPRY2), protein phosphatase 2A (PP2A), and phosphatase and tensin homolog (PTEN), are commonly inactivated in prostate cancer. The molec...

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Autores principales: Patel, Rachana, Gao, Meiling, Ahmad, Imran, Fleming, Janis, Singh, Lukram B., Rai, Taranjit Singh, McKie, Arthur B., Seywright, Morag, Barnetson, Robert J., Edwards, Joanne, Sansom, Owen J., Leung, Hing Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582117/
https://ncbi.nlm.nih.gov/pubmed/23434594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63672
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