Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression

Concurrent activation of RAS/ERK and PI3K/AKT pathways is implicated in prostate cancer progression. The negative regulators of these pathways, including sprouty2 (SPRY2), protein phosphatase 2A (PP2A), and phosphatase and tensin homolog (PTEN), are commonly inactivated in prostate cancer. The molec...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Patel, Rachana, Gao, Meiling, Ahmad, Imran, Fleming, Janis, Singh, Lukram B., Rai, Taranjit Singh, McKie, Arthur B., Seywright, Morag, Barnetson, Robert J., Edwards, Joanne, Sansom, Owen J., Leung, Hing Y.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582117/
https://ncbi.nlm.nih.gov/pubmed/23434594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63672
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