Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges. Deregulated receptor tyrosine kinase (RTK) signalling mediated by loss of tumour suppressor Sprouty2 (SPRY2) is associated with treatment resi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO Mol Med
Hlavní autoři: Patel, Rachana, Fleming, Janis, Mui, Ernest, Loveridge, Carolyn, Repiscak, Peter, Blomme, Arnaud, Harle, Victoria, Salji, Mark, Ahmad, Imran, Teo, Katy, Hamdy, Freddie C, Hedley, Ann, van den Broek, Niels, Mackay, Gillian, Edwards, Joanne, Sansom, Owen J, Leung, Hing Y
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887544/
https://ncbi.nlm.nih.gov/pubmed/29540470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708347
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky