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Key Role of Group V Secreted Phospholipase A(2) in Th2 Cytokine and Dendritic Cell-Driven Airway Hyperresponsiveness and Remodeling
BACKGROUND: Previous work has shown that disruption of the gene for group X secreted phospholipase A(2) (sPLA(2)-X) markedly diminishes airway hyperresponsiveness and remodeling in a mouse asthma model. With the large number of additional sPLA(2)s in the mammalian genome, the involvement of other sP...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581544/ https://ncbi.nlm.nih.gov/pubmed/23451035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056172 |
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