Key Role of Group V Secreted Phospholipase A(2) in Th2 Cytokine and Dendritic Cell-Driven Airway Hyperresponsiveness and Remodeling

BACKGROUND: Previous work has shown that disruption of the gene for group X secreted phospholipase A(2) (sPLA(2)-X) markedly diminishes airway hyperresponsiveness and remodeling in a mouse asthma model. With the large number of additional sPLA(2)s in the mammalian genome, the involvement of other sP...

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Detalhes bibliográficos
Main Authors: Henderson Jr, William R., Ye, Xin, Lai, Ying, Ni, Zhanglin, Bollinger, James G., Tien, Ying-Tzang, Chi, Emil Y., Gelb, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581544/
https://ncbi.nlm.nih.gov/pubmed/23451035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056172
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