Secreted Phospholipase A(2) Group X Overexpression in Asthma and Bronchial Hyperresponsiveness

Rationale: Secreted phospholipase A(2) enzymes (sPLA(2)s) play key regulatory roles in the biosynthesis of eicosanoids, such as the cysteinyl leukotrienes, but the role of these enzymes in the pathogenesis of asthma is not known. Objectives: To establish if sPLA(2)s are overexpressed in the airways...

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Главные авторы: Hallstrand, Teal S., Chi, Emil Y., Singer, Alan G., Gelb, Michael H., Henderson, William R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2007
Предметы:
A. Asthma and Allergy
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176098/
https://ncbi.nlm.nih.gov/pubmed/17901411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200707-1088OC
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