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Secreted Phospholipase A(2) Group X Overexpression in Asthma and Bronchial Hyperresponsiveness

Rationale: Secreted phospholipase A(2) enzymes (sPLA(2)s) play key regulatory roles in the biosynthesis of eicosanoids, such as the cysteinyl leukotrienes, but the role of these enzymes in the pathogenesis of asthma is not known. Objectives: To establish if sPLA(2)s are overexpressed in the airways...

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Hlavní autoři: Hallstrand, Teal S., Chi, Emil Y., Singer, Alan G., Gelb, Michael H., Henderson, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176098/
https://ncbi.nlm.nih.gov/pubmed/17901411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200707-1088OC
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