SON Protein Regulates GATA-2 through Transcriptional Control of the MicroRNA 23a∼27a∼24-2 Cluster

SON is a DNA- and RNA-binding protein localized in nuclear speckles. Although its function in RNA splicing for effective cell cycle progression and genome stability was recently unveiled, other mechanisms of SON functions remain unexplored. Here, we report that SON regulates GATA-2, a key transcript...

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Detalhes bibliográficos
Main Authors: Ahn, Erin Eun-Young, Higashi, Tsunehito, Yan, Ming, Matsuura, Shinobu, Hickey, Christopher J., Lo, Miao-Chia, Shia, Wei-Jong, DeKelver, Russell C., Zhang, Dong-Er
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581430/
https://ncbi.nlm.nih.gov/pubmed/23322776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447227
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