Gating Transitions in the Palm Domain of ASIC1a

Acid-sensing ion channels (ASICs) are trimeric cation-selective proton-gated ion channels expressed in the central and peripheral nervous systems. The pore-forming transmembrane helices in these channels are linked by short loops to the palm domain in the extracellular region. Here, we explore the c...

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Bibliographic Details
Main Authors: Della Vecchia, Margaret C., Rued, Anna C., Carattino, Marcelo D.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581397/
https://ncbi.nlm.nih.gov/pubmed/23300086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441964
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