The MLK-related Kinase (MRK) Is a Novel RhoC Effector That Mediates Lysophosphatidic Acid (LPA)-stimulated Tumor Cell Invasion

The small GTPase RhoC is overexpressed in many invasive tumors and is essential for metastasis. Despite its high structural homology to RhoA, RhoC appears to perform functions that are different from those controlled by RhoA. The identity of the signaling components that are differentially regulated...

Full description

Saved in:
Bibliographic Details
Main Authors: Korkina, Olga, Dong, Zhiwan, Marullo, Allison, Warshaw, Gregg, Symons, Marc, Ruggieri, Rosamaria
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581392/
https://ncbi.nlm.nih.gov/pubmed/23319595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.414060
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items