The MLK-related Kinase (MRK) Is a Novel RhoC Effector That Mediates Lysophosphatidic Acid (LPA)-stimulated Tumor Cell Invasion

The small GTPase RhoC is overexpressed in many invasive tumors and is essential for metastasis. Despite its high structural homology to RhoA, RhoC appears to perform functions that are different from those controlled by RhoA. The identity of the signaling components that are differentially regulated...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Korkina, Olga, Dong, Zhiwan, Marullo, Allison, Warshaw, Gregg, Symons, Marc, Ruggieri, Rosamaria
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2013
الموضوعات:
Signal Transduction
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581392/
https://ncbi.nlm.nih.gov/pubmed/23319595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.414060
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