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SmgGDS Is a Guanine Nucleotide Exchange Factor That Specifically Activates RhoA and RhoC
SmgGDS is an atypical guanine nucleotide exchange factor (GEF) that promotes both cell proliferation and migration and is up-regulated in several types of cancer. SmgGDS has been previously shown to activate a wide variety of small GTPases, including the Ras family members Rap1a, Rap1b, and K-Ras, a...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069418/ https://ncbi.nlm.nih.gov/pubmed/21242305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191122 |
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