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The MLK-related Kinase (MRK) Is a Novel RhoC Effector That Mediates Lysophosphatidic Acid (LPA)-stimulated Tumor Cell Invasion

The small GTPase RhoC is overexpressed in many invasive tumors and is essential for metastasis. Despite its high structural homology to RhoA, RhoC appears to perform functions that are different from those controlled by RhoA. The identity of the signaling components that are differentially regulated...

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Detalhes bibliográficos
Main Authors: Korkina, Olga, Dong, Zhiwan, Marullo, Allison, Warshaw, Gregg, Symons, Marc, Ruggieri, Rosamaria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581392/
https://ncbi.nlm.nih.gov/pubmed/23319595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.414060
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