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The action of selective CRAC channel blockers is affected by the Orai pore geometry
As the molecular composition of calcium-release activated calcium (CRAC) channels has been unknown for two decades, elucidation of selective inhibitors has been considerably hampered. By the identification of the two key components of CRAC channels, STIM1 and Orai1 have emerged as promising targets...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580291/ https://ncbi.nlm.nih.gov/pubmed/23218667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2012.11.005 |
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