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The Lumenal Loop M672-P707 of the Menkes Protein (ATP7A) Transfers Copper to Peptidylglycine Monooxygenase

Copper transfer to cuproproteins located in vesicular compartments of the secretory pathway depends on activity of the copper translocating ATPase (ATP7A or ATP7B) but the mechanism of transfer is largely unexplored. Copper-ATPase ATP7A is unique in having a sequence rich in histidine and methionine...

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Autores principales: Otoikhian, Adenike, Barry, Amanda N., Mayfield, Mary, Nilges, Mark, Huang, Yiping, Lutsenko, Svetlana, Blackburn, Ninian J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580079/
https://ncbi.nlm.nih.gov/pubmed/22577880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301221s
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