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Neutralizing Antibodies Induced by Recombinant Virus-Like Particles of Enterovirus 71 Genotype C4 Inhibit Infection at Pre- and Post-attachment Steps
BACKGROUND: Enterovirus 71 (EV71) is a major causative agent of hand, foot and mouth disease, which has been prevalent in Asia–Pacific regions, causing significant morbidity and mortality in young children. Antibodies elicited by experimental EV71 vaccines could neutralize infection in vitro and pas...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579802/ https://ncbi.nlm.nih.gov/pubmed/23451250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057601 |
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