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Neutralizing Antibodies Induced by Recombinant Virus-Like Particles of Enterovirus 71 Genotype C4 Inhibit Infection at Pre- and Post-attachment Steps

BACKGROUND: Enterovirus 71 (EV71) is a major causative agent of hand, foot and mouth disease, which has been prevalent in Asia–Pacific regions, causing significant morbidity and mortality in young children. Antibodies elicited by experimental EV71 vaccines could neutralize infection in vitro and pas...

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Detalhes bibliográficos
Main Authors: Ku, Zhiqiang, Ye, Xiaohua, Huang, Xulin, Cai, Yicun, Liu, Qingwei, Li, Yan, Su, Zhiguo, Huang, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579802/
https://ncbi.nlm.nih.gov/pubmed/23451250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057601
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