Chimeric Virus-Like Particle Vaccines Displaying Conserved Enterovirus 71 Epitopes Elicit Protective Neutralizing Antibodies in Mice through Divergent Mechanisms

Enterovirus 71 (EV71) is a major causative agent of hand, food, and mouth disease, which frequently occurs in young children. Since there are 11 subgenotypes (A, B1 to B5, and C1 to C5) within EV71, an EV71 vaccine capable of protecting against all of these subgenotypes is desirable. We report here...

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Bibliografiska uppgifter
Huvudupphovsmän: Ye, Xiaohua, Ku, Zhiqiang, Liu, Qingwei, Wang, Xiaoli, Shi, Jinping, Zhang, Yunfang, Kong, Liangliang, Cong, Yao, Huang, Zhong
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911748/
https://ncbi.nlm.nih.gov/pubmed/24131712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01848-13
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