Chimeric Virus-Like Particle Vaccines Displaying Conserved Enterovirus 71 Epitopes Elicit Protective Neutralizing Antibodies in Mice through Divergent Mechanisms

Enterovirus 71 (EV71) is a major causative agent of hand, food, and mouth disease, which frequently occurs in young children. Since there are 11 subgenotypes (A, B1 to B5, and C1 to C5) within EV71, an EV71 vaccine capable of protecting against all of these subgenotypes is desirable. We report here...

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Detalhes bibliográficos
Main Authors: Ye, Xiaohua, Ku, Zhiqiang, Liu, Qingwei, Wang, Xiaoli, Shi, Jinping, Zhang, Yunfang, Kong, Liangliang, Cong, Yao, Huang, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911748/
https://ncbi.nlm.nih.gov/pubmed/24131712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01848-13
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