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Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody

Enterovirus 71 (EV71) is the main pathogen responsible for hand, foot and mouth disease with severe neurological complications and even death in young children. We have recently identified a highly potent anti-EV71 neutralizing monoclonal antibody, termed D5. Here we investigated the structural basi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Principais autores: Ye, Xiaohua, Fan, Chen, Ku, Zhiqiang, Zuo, Teng, Kong, Liangliang, Zhang, Chao, Shi, Jinping, Liu, Qingwei, Chen, Tan, Zhang, Yingyi, Jiang, Wen, Zhang, Linqi, Huang, Zhong, Cong, Yao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777393/
https://ncbi.nlm.nih.gov/pubmed/26938634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005454
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