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Probing GPCR Structure: Adenosine and P2Y Nucleotide Receptors

The adenosine receptors (ARs) provide an example of how to accurately predict ligand recognition, even prior to the availability of a crystallographic structure. Homology modeling has been used to gain structural insight, in conjunction with site-directed mutagenesis and structure activity relations...

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Hlavní autoři: Jacobson, Kenneth A., Costanzi, Stefano, Deflorian, Francesca
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579568/
https://ncbi.nlm.nih.gov/pubmed/23332701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-391861-1.00009-5
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