4-Alkyloxyimino-cytosine nucleotides: tethering approaches to molecular probes for the P2Y(6) receptor()

4-Alkyloxyimino derivatives of pyrimidine nucleotides display high potency as agonists of certain G protein-coupled P2Y receptors (P2YRs). In an effort to functionalize a P2Y(6)R agonist for fluorescent labeling, we probed two positions (N(4) and γ-phosphate of cytidine derivatives) with various fun...

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Veröffentlicht in:Medchemcomm
Hauptverfasser: Jayasekara, P. Suresh, Barrett, Matthew O., Ball, Christopher B., Brown, Kyle A., Kozma, Eszter, Costanzi, Stefano, Squarcialupi, Lucia, Balasubramanian, Ramachandran, Maruoka, Hiroshi, Jacobson, Kenneth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493932/
https://ncbi.nlm.nih.gov/pubmed/26161252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00132F
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