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Comparison of three GPCR structural templates for modeling of the P2Y(12) nucleotide receptor
The P2Y(12) receptor (P2Y(12)R) is an ADP-activated G protein-coupled receptor (GPCR) that is an important target for antithrombotic drugs. Three homology models of P2Y(12)R were compared, based on different GPCR structural templates: bovine rhodopsin (bRHO), human A(2A) adenosine receptor (A(2A)AR)...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157290/ https://ncbi.nlm.nih.gov/pubmed/21461952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-011-9423-3 |
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