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Purine Receptors: GPCR Structure and Agonist Design

An integrated approach to the study of drug-receptor interactions has been applied to adenosine receptors (ARs) and P2Y nucleotide receptors. This approach includes probing the receptor structure through site-directed mutagenesis and molecular modeling, in concert with altering the structure of the...

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Detalhes bibliográficos
Main Authors: Jacobson, Kenneth A., Kim, Soo-Kyung, Costanzi, Stefano, Gao, Zhan-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418328/
https://ncbi.nlm.nih.gov/pubmed/15616163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.4.6.7
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