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Docking studies of agonists and antagonists suggest an activation pathway of the A(3) adenosine receptor

Structural determinants of ligand efficacy in the human A(3) adenosine receptor (AR) were studied using pharmacophore and docking analyses of various categories of A(3) selective ligands: inverse agonist, neutral antagonist (nonnucleoside and nucleoside), and agonist (partial and full). The homology...

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Detalhes bibliográficos
Publicado no:J Mol Graph Model
Main Authors: Kim, Soo-Kyung, Gao, Zhan-Guo, Jeong, Lak Shin, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262875/
https://ncbi.nlm.nih.gov/pubmed/16793299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2006.05.004
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