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Characteristics of the turnover of uncoupling protein 3 by the ubiquitin proteasome system in isolated mitochondria

Uncoupling protein 3 (UCP3) is implicated in mild uncoupling and the regulation of mitochondrial ROS production. We previously showed that UCP3 turns over rapidly in C2C12 myoblasts, with a half-life of 0.5–4 h, and that turnover can be reconstituted in vitro. We show here that rapid degradation of...

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Main Authors: Mookerjee, Shona A., Brand, Martin D.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578713/
https://ncbi.nlm.nih.gov/pubmed/21820402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2011.07.011
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