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Characteristics of the turnover of uncoupling protein 3 by the ubiquitin proteasome system in isolated mitochondria
Uncoupling protein 3 (UCP3) is implicated in mild uncoupling and the regulation of mitochondrial ROS production. We previously showed that UCP3 turns over rapidly in C2C12 myoblasts, with a half-life of 0.5–4 h, and that turnover can be reconstituted in vitro. We show here that rapid degradation of...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578713/ https://ncbi.nlm.nih.gov/pubmed/21820402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2011.07.011 |
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