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Rapid turnover of mitochondrial uncoupling protein 3

UCP3 (uncoupling protein 3) and its homologues UCP2 and UCP1 are regulators of mitochondrial function. UCP2 is known to have a short half-life of approx. 1 h, owing to its rapid degradation by the cytosolic 26S proteasome, whereas UCP1 is turned over much more slowly by mitochondrial autophagy. In t...

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Hlavní autoři: Azzu, Vian, Mookerjee, Shona A., Brand, Martin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661275/
https://ncbi.nlm.nih.gov/pubmed/19954423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091321
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