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The on/off switches of the mitochondrial uncoupling proteins

Mitochondrial uncoupling proteins disengage substrate oxidation from ADP phosphorylation by dissipating the proton electrochemical gradient that is required for ATP synthesis. In doing this, the archetypal uncoupling protein, UCP1, mediates adaptive thermogenesis. By contrast, its paralogues UCP2 an...

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Bibliografske podrobnosti
Main Authors: Azzu, Vian, Brand, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640847/
https://ncbi.nlm.nih.gov/pubmed/20006514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2009.11.001
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