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Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2

Glucose intolerance in C57Bl/6 mice has been associated with mutations in the nicotinamide nucleotide transhydrogenase (Nnt) gene. It has been proposed that the absence of NNT from mitochondria leads to increased mitochondrial reactive oxygen species production and subsequent activation of uncouplin...

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Detalhes bibliográficos
Main Authors: Parker, Nadeene, Vidal-Puig, Antonio J., Azzu, Vian, Brand, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741566/
https://ncbi.nlm.nih.gov/pubmed/19539600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.06.005
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