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Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation
The hematopoietic humanized mouse (hu-mouse) model is a powerful resource to study and manipulate the human immune system. However, a major and recurrent issue with this model has been the poor maturation of B cells that fail to progress beyond the transitional B cell stage. Interestingly, a similar...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578183/ https://ncbi.nlm.nih.gov/pubmed/23335750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202810 |
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