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Mouse marginal zone B cells harbor specificities similar to human broadly neutralizing HIV antibodies

A series of potent, broadly neutralizing HIV antibodies have been isolated from B cells of HIV-infected individuals. VRC01 represents a subset of these antibodies that mediate neutralization with a restricted set of IGHV genes. The memory B cells expressing these antibodies were isolated years after...

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Hlavní autoři: Pujanauski, Lindsey M., Janoff, Edward N., McCarter, Martin D., Pelanda, Roberta, Torres, Raul M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557101/
https://ncbi.nlm.nih.gov/pubmed/23288906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213713110
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