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A Reduced Zinc Diet or Zinc Transporter 3 Knockout Attenuate Light Induced Zinc Accumulation and Retinal Degeneration
Our previous study on retinal light exposure suggests the involvement of zinc (Zn(2+)) toxicity in the death of RPE and photoreceptors (LD) which could be attenuated by pyruvate and nicotinamide, perhaps through restoration of NAD(+) levels. In the present study, we examined Zn(2+) toxicity, and the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578048/ https://ncbi.nlm.nih.gov/pubmed/23274584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.12.008 |
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