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Light-induced photoreceptor and RPE degeneration involve zinc toxicity and are attenuated by pyruvate, nicotinamide, or cyclic light

PURPOSE: Light-induced damage can be a problem after surgery or sun exposure. Short-duration, intense light causes preferential photoreceptor death in the superior central retina of albino mice and rats and serves as a model of oxidation-induced neurodegeneration. Previous work on retinal ischemia-i...

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Autores principales: Sheline, Christian T., Zhou, Yongdong, Bai, Shi
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Vision 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002969/
https://ncbi.nlm.nih.gov/pubmed/21179242
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