Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahyroquinoline Library

[Image: see text] A 2328-membered library of 2,3,4-trisubstituted tetrahydroquinolines was produced using a combination of solution- and solid-phase synthesis techniques. A tetrahydroquinoline (THQ) scaffold was prepared via an asymmetric Povarov reaction using cooperative catalysis to generate thre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gerard, Baudouin, O’Shea, Morgan Welzel, Donckele, Etienne, Kesavan, Sarathy, Akella, Lakshmi B., Xu, Hao, Jacobsen, Eric N., Marcaurelle, Lisa A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577964/
https://ncbi.nlm.nih.gov/pubmed/23088641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co300098v
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge