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Asymmetric Cooperative Catalysis of Strong Brønsted Acid-Promoted Reactions Using Chiral Ureas

Cationic organic intermediates participate in a wide variety of useful synthetic transformations, but their high reactivity can render selectivity in competing pathways difficult to control. We describe a strategy for inducing enantioselectivity in reactions of protio-iminium ions, wherein a chiral...

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Detalhes bibliográficos
Main Authors: Xu, Hao, Zuend, Stephan J., Woll, Matthew G., Tao, Ye, Jacobsen, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993568/
https://ncbi.nlm.nih.gov/pubmed/20167783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1182826
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