Ca(2+)-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle

Excessive increases in intracellular [Ca(2+)] in skeletal muscle fibres cause failure of excitation–contraction coupling by disrupting communication between the dihydropyridine receptors in the transverse tubular system and the Ca(2+) release channels (RyRs) in the sarcoplasmic reticulum (SR), but t...

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Bibliographic Details
Main Authors:	Murphy, R M, Dutka, T L, Horvath, D, Bell, J R, Delbridge, L M, Lamb, G D
Format:	Artigo
Language:	Inglês
Published:	Blackwell Science Inc 2013
Subjects:	Skeletal Muscle and Exercise
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3577539/ https://ncbi.nlm.nih.gov/pubmed/23148318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.243279
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Ca(2+)-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle

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