S-Glutathionylation of troponin I (fast) increases contractile apparatus Ca(2+) sensitivity in fast-twitch muscle fibres of rats and humans

Oxidation can decrease or increase the Ca(2+) sensitivity of the contractile apparatus in rodent fast-twitch (type II) skeletal muscle fibres, but the reactions and molecular targets involved are unknown. This study examined whether increased Ca(2+) sensitivity is due to S-glutathionylation of parti...

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Autores principales: Mollica, J P, Dutka, T L, Merry, T L, Lamboley, C R, McConell, G K, McKenna, M J, Murphy, R M, Lamb, G D
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2012
Materias:
Skeletal Muscle and Exercise
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382333/
https://ncbi.nlm.nih.gov/pubmed/22250211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.224535
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