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Calsequestrin content and SERCA determine normal and maximal Ca(2+) storage levels in sarcoplasmic reticulum of fast- and slow-twitch fibres of rat

Whilst calsequestrin (CSQ) is widely recognized as the primary Ca(2+) buffer in the sarcoplasmic reticulum (SR) in skeletal muscle fibres, its total buffering capacity and importance have come into question. This study quantified the absolute amount of CSQ isoform 1 (CSQ1, the primary isoform) prese...

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Библиографические подробности
Главные авторы: Murphy, Robyn M, Larkins, Noni T, Mollica, Janelle P, Beard, Nicole A, Lamb, Graham D
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670055/
https://ncbi.nlm.nih.gov/pubmed/19029185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.163162
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