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Modulation of contractile apparatus Ca(2+) sensitivity and disruption of excitation–contraction coupling by S-nitrosoglutathione in rat muscle fibres

ABSTRACT: S-Nitrosoglutathione (GSNO) is generated in muscle and may S-glutathionylate and/or S-nitrosylate various proteins involved in excitation–contraction (EC) coupling, such as Na(+)-K(+)-ATPases, voltage-sensors (VSs) and Ca(2+) release channels (ryanodine receptors, RyRs), possibly changing...

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Detalhes bibliográficos
Main Authors: Dutka, T L, Mollica, J P, Posterino, G S, Lamb, G D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098697/
https://ncbi.nlm.nih.gov/pubmed/21115647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.200451
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