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Ca(2+)-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle
Excessive increases in intracellular [Ca(2+)] in skeletal muscle fibres cause failure of excitation–contraction coupling by disrupting communication between the dihydropyridine receptors in the transverse tubular system and the Ca(2+) release channels (RyRs) in the sarcoplasmic reticulum (SR), but t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577539/ https://ncbi.nlm.nih.gov/pubmed/23148318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.243279 |
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