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Ca(2+) activation of diffusible and bound pools of μ-calpain in rat skeletal muscle

Skeletal muscle fibres contain ubiquitous and muscle-specific calcium-dependent proteases known as calpains. During normal activity, intracellular [Ca(2+)] in muscle fibres increases to high levels (∼2–20 μm), and it is not apparent how this can be reconciled with the activation properties of the ca...

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Autors principals: Murphy, Robyn M, Verburg, Esther, Lamb, Graham D
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890353/
https://ncbi.nlm.nih.gov/pubmed/16857710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.114090
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