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Adeno-associated Virus Serotype 8 (AAV8) Delivery of Recombinant A20 to Skeletal Muscle Reduces Pathological Activation of Nuclear Factor (NF)-κB in Muscle of mdx Mice

Duchenne muscular dystrophy (DMD) is a genetic muscle disease caused by the absence of a functional dystrophin protein. Lack of dystrophin protein disrupts the dystrophin-glycoprotein complex causing muscle membrane instability and degeneration. One of the secondary manifestations resulting from lac...

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Detalhes bibliográficos
Main Authors: Charan, Rakshita A, Niizawa, Gabriela, Nakai, Hiroyuki, Clemens, Paula R
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576473/
https://ncbi.nlm.nih.gov/pubmed/23154638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00299
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