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Inhibition of the IKK/NF-κB Pathway by AAV Gene Transfer Improves Muscle Regeneration in Older mdx Mice
The IκB kinase (IKKα, β and the regulatory subunit IKKγ) complex regulates nuclear factor of κB (NF-κB) transcriptional activity, which is upregulated in many chronic inflammatory diseases. NF-κB signaling promotes inflammation and limits muscle regeneration in Duchenne muscular dystrophy (DMD), res...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471137/ https://ncbi.nlm.nih.gov/pubmed/20720575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.110 |
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