Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation

Nuclear factor κB (NF-κB) is a transcription factor important for regulating innate and adaptive immunity, cellular proliferation, apoptosis, and senescence. Dysregulation of NF-κB and its upstream regulator IκB kinase (IKK) contributes to the pathogenesis of multiple inflammatory and degenerative d...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS Biol
Autors principals: Zhao, Jing, Zhang, Lei, Mu, Xiaodong, Doebelin, Christelle, Nguyen, William, Wallace, Callen, Reay, Daniel P., McGowan, Sara J., Corbo, Lana, Clemens, Paula R., Wilson, Gabriela Mustata, Watkins, Simon C., Solt, Laura A., Cameron, Michael D., Huard, Johnny, Niedernhofer, Laura J., Kamenecka, Theodore M., Robbins, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013238/
https://ncbi.nlm.nih.gov/pubmed/29889904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2004663
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars