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Interleukin-1-induced NF-κB Activation Is NEMO-dependent but Does Not Require IKKβ

Activation of NF-κB by the pro-inflammatory cytokines tumor necrosis factor (TNF) and interleukin-1 (IL-1) requires the IκB kinase (IKK) complex, which contains two kinases named IKKα and IKKβ and a critical regulatory subunit named NEMO. Although we have previously demonstrated that NEMO associates...

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Bibliografiske detaljer
Main Authors: Solt, Laura A., Madge, Lisa A., Orange, Jordan S., May, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824644/
https://ncbi.nlm.nih.gov/pubmed/17244613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609613200
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