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Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies

Adeno-associated viruses (AAVs) are promising viral vectors for therapeutic gene delivery, and the approval of an AAV1 vector for the treatment of lipoprotein lipase deficiency has heralded a new and exciting era for this system. However, preclinical and clinical studies show that neutralization fro...

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Detalhes bibliográficos
Publicado no:J Virol Methods
Main Authors: Tseng, Yu-Shan, Van Vliet, Kim, Rao, Lavanya, McKenna, Robert, Byrne, Barry J., Asokan, Aravind, Agbandje-McKenna, Mavis
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011015/
https://ncbi.nlm.nih.gov/pubmed/27424005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2016.07.009
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