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RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes
During V(D)J recombination, recombination activating gene proteins RAG1 and RAG2 generate DNA double strand breaks within a paired complex (PC) containing two complementary recombination signal sequences (RSSs), the 12RSS and 23RSS, which differ in the length of the spacer separating heptamer and no...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575807/ https://ncbi.nlm.nih.gov/pubmed/23293004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1294 |
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